Eve is featured (along with Erykah Badu) on the song "You Got Me" by The Roots, from their 1999 album Things Fall Apart.
The song won a Grammy Award in 2000, which should have been Eve's first.
The same year, she appeared on the official remix of Amerie's number one U. R&B hit, "1 Thing" (featured on the Hitch soundtrack).
Dre, so she collaborated with DMX and the Ruff Ryders on her first single as a Ruff Ryder DJ Clue? Ruff Ryders' First Lady, was an unprecedented success, making it the third album by a female rap artist to top the Billboard 200, behind Lauryn Hill's The Miseducation of Lauryn Hill (1998) and Foxy Brown's Chyna Doll (1999).
The song won a Grammy Award for Best Rap/Sung Collaboration, and Eve eventually went platinum.
One of the record's strengths, cited in several reviews, was Eve's exploration of her singing voice in addition to her rapping skills.
The follow-up to Ruff Ryders' First Lady, Scorpion, was released in 2001.
Its first single, "Who's That Girl" guaranteed the rapper first international success.